Lab Mission
Branching into equity: uncovering hidden biological variables to optimize cancer treatment.
Branch 1: Roots of Resistance
We investigate the fundamental biological barriers to effective cancer treatment, including genetic mutations, cell kinetics, and microenvironmental factors such as hypoxia. Our work spans from pioneering gene-based systems targeting hypoxic tumor compartments to identifying markers of hypoxic signaling and establishing mechanistic foundations of radioresistance. By making these hidden drivers measurable and actionable, we aim to dismantle resistance at its roots and improve treatment precision.
Branch 2: Pathways to Precision and Equity
This branch integrates predictive modeling with biological equity. We develop tools and frameworks that incorporate sex-linked biology, genetic signatures, and tumor-response modeling into precision oncology. Our research exposes systemic gaps in sex-specific analysis, demonstrates how male–female divergence affects biomarker performance, and builds predictive systems that ensure treatments are tailored to individual biology. By combining analytics and equity, we aim to optimize cancer care for every patient.